SPECIAL SYMPOSIUM: Ann McKee, MD

Updates in Chronic Traumatic Encephalopathy #334313

CONCURRENT SESSION BLOCK 8
SAT 28 OCT // 11:30 AM – 12:45 PM

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Kristen Dams-O’Connor

“I was thrilled to learn Dr. McKee would be joining us at ACRM this year. Her program of research is informing opportunities for detection, management and prevention of brain injury, which is highly relevant to rehabilitation professionals.”

 

—Kristen Dams-O’Connor, PhD

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PRESENTER

Ann McKee, MD
Director, CTE Center, VA Medical Center
Professor of Neurology & Pathology, Boston University

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As seen on TODAY SHOW

As seen in New York Times

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FOCUS AREA

Brain Injury

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DESCRIPTION

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative brain disease found in athletes and military personnel with history of repetitive brain trauma, including symptomatic concussions as well as asymptomatic subconcussive hits to the head. CTE has been known to affect boxers since the 1920s. However, recent reports have been published of neuropathologically confirmed CTE in athletes who have a history of repetitive brain trauma. Dr. McKee will describe the neuropathological changes associated with CTE. She’ll also highlight the neuropathological differences between CTE and other neurodegenerative diseases. Furthermore, she’ll describe the clinical changes associated with CTE and discuss her current research.

 

LEARNING OBJECTIVES:

1. The learner will be able to describe the neuropathological changes associated with Chronic Traumatic Encephalopathy (CTE)
   1. Content: Present multiple clinicopathological cases of CTE

2. The learner will be able to update on the neuropathological difference and similarities between CTE and other diseases such as Alzheimer’s disease and ALS
   1. Assess clinical implications of this area of research.

3. The learner will be able to describe the clinical and neuropathological changes associated with neurodegeneration after single traumatic brain injury.
   1. Present several clinicopathological cases of neurodegeneration after single TBI.

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ABOUT DR. McKee

Dr. McKee completed her undergraduate studies at the University of Wisconsin and received her medical degree from the Case Western Reserve School of Medicine. She completed residency training in neurology at Cleveland Metropolitan General Hospital and fellowship training in neuropathology at Massachusetts General Hospital. She is Professor of Neurology and Pathology at BU School of Medicine. Dr. McKee directs the Neuropathology Service for the New England Veterans Administration Medical Centers (VISN-1) and the Brain Banks for the Boston University Alzheimer’s Disease Center, Chronic Traumatic Encephalopathy Center, and Framingham Heart Study.

Dr. McKee’s research interests center on the neuropathological alterations of neurodegenerative diseases, with a primary focus on the role of tau protein, axonal injury, trauma, vascular injury, and neurodegeneration. Much of her current work centers on mild traumatic brain injury from contact sports and military service and its long-term consequences. As a board-certified neurologist and neuropathologist, she is particularly interested in the clinical, behavioral and psychological manifestations of pathological disease and the neuroanatomical localization of clinical symptoms. She has written widely on many neurodegenerative diseases including Alzheimer’s disease and Chronic Traumatic Encephalopathy (CTE). Dr. McKee has received numerous awards for her work and has been essential in establishing the clinical and pathological criteria for the diagnosis of CTE. In addition, she organized the First NINDS Consensus Conference to determine the Neuropathological Criteria for CTE, Boston, MA February 25-27, 2015 http://www.ninds.nih.gov/research/tbi/ReportFirstNIHConsensusConference.htm). The second installment of the meeting brought together additional researchers in Boston from November 14-16, 2016. At the first meeting, the consensus panel defined the pathognomonic lesion of CTE; at the second, the panel began working on the staging criteria for CTE. This ongoing project will continue to identify the unique pathology of CTE and allow researchers across the world to work in partnership to help those suffering from the long-term effects of head trauma.

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Douglas Katz

“We are excited to have Dr. Ann McKee, a leading authority on chronic traumatic encephalopathy, to present results from her studies. She has led the effort in defining the neuropathology of this degenerative disorder that can affect athletes, soldiers and others who experience repetitive head trauma.”

—Douglas Katz, MD, FACRM, FAAN, FANA, FASNR

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