Neuropharmacology #124

MON, 31 OCT // 1:30 PM – 5:30 PM

Primary Content Focus: Crosscutting (Neuro-Pharmacology)

Secondary Content Focus: Brain Injury, Clinical practice (assessment, diagnosis, treatment, knowledge translation/EBP)

This course surveys the basic principles of neuropharmacology with an emphasis on the molecular pharmacology of drugs used to treat CNS disorders which are of particular interest to Rehabilitation Medicine Practioners. The course will provide a description of the cellular and molecular actions of drugs on synaptic transmission with discussion of drug-induced changes in functioning of the nervous system. We will examine how the neurotransmitter systems influence nervous system as well as therapeutic targets affecting these transmitter systems. Issues surrounding drug entry into the central nervous system will be addressed. Clinical applications of neuropharmacology, the link between neuropharmacology and behavior, and current research investigating the development of drugs for neuronal targets will be addressed.

This course is specifically oriented with a clinical and evidence-based practice model in mind, and will draw upon the experience and expertise of senior clinicians, combined with thorough theoretical discussions involving both early and established clinicians.
This course is designed to provide a foundation for advanced knowledge in neuro-psychopharmacology, and to provide an introduction to the pharmacological treatment of CNS pathologies. The ultimate goal is to understand how molecular neuroscience can guide the direction of basic medical science and therapeutic approaches.

LEARNING OBJECTIVES

Clinical Practice Oriented discussion of Neuro-pharmacology: Drugs and Receptors, mechanism of action etc.
Specific emphasis on Neuro-pharmacology related to common conditions encountered in Rehabilitation Practice
Evidence-based references and simulated/hypothetical clinical scenarios to explain concepts
Targeted at both Early Career and Established persons
To develop an appreciation of the need for further research to identify new drug targets for more effective therapies.

KEY WORDS

Neuropharmacology
Cognitive Neuroscience
Traumatic Brain Injury
Behavioural Science
Neuroimmunology

FACULTY

Arshia Ahmad, MD, MRCP (UK), MSc Clinical Neurology
Assistant Professor PM&R, IUPUI

Dr. Ahmad is a neurologist trained in UK, with an MD, MRCP ( Membership of the Royal College of Physicians, UK) and a Masters in Clinical Neurology from University of London and Assistant Professor PM&R at IUPUI. Being an early career Rehab Physician, he is actively involved in ACRM, and had the honor of presenting a 75 min symposium at the Oct 2015 Annual Conference. For the past 2 years he has been working on a project to Bridge the Gap in Brain Injury Management and Rehabilitation in developing countries. In addition to financial issues there are socio-policital and cultural factors that influence how brain injuries are managed in developing countries which have seen an increase in the brain injuries in the last decades due to war on terror and natural disasters. To bridge these gaps Dr. Ahmad is working in collaboration with Armed Forces Institute of Rehab Medicine in Isalamabad, Pakistan. She is also visiting faculty at Shaheed Zulfiqar Ali Bhutto University in Islamabad Pakistan. In this role, she has been delivering training workshops and lectures to medics and paramedics to increase the knowledge base and give them comparative practice guidelines from all over the world. This is technical knowledge transfer and is geared towards formulating national management guidelines. In addition, Dr. Ahmad has also been speaking and writing at public forums to increase general public awareness about brain injury management and rehabilitation.

Douglas Katz, MD, FACRM, FAAN, FANA
Professor and Medical Director of ABI, Boston University / Braintree Rehabilitation Hospital

Dr. Katz is Professor of Neurology at Boston University School of Medicine, a member of the academic neurology staff at Boston Medical Center and Medical Director of the Brain Injury Program at Braintree Rehabilitation Hospital in Massachusetts. With subspecialties in cognitive/behavioral neurology and neurorehabilitation, he is a recognized expert and leader in the field of traumatic brain injury (TBI) rehabilitation with over 29 years of experience in TBI clinical care, clinical research, education and program development. His research and publications have included studies of neuropathology, natural history and outcome prediction in TBI, disorders of consciousness after brain injury, pharmacologic treatment of cognitive problems after TBI, and structural and functional imaging in relation to recovery and rehabilitation after TBI. Dr. Katz has served on a number of boards of organizations involved in brain injury and neurorehabilitation including the American Congress of Rehabilitation Medicine, Brain Injury Association of America, American Society of Neurorehabilitation and MAB Community Services. He is President of the American Congress of Rehabilitation Medicine, 2015-2017.

Min JeongPark, MD
Staff Physiatrist, Hennepin County Medical School

Min Jeong Park obtained her Doctor of Medicine degree at Jeju National University School of Medicine in South Korea in 2007. She completed her residency in Physical Medicine and Rehabilitation at Montefiore Medical Center/Albert Einstein College of Medicine in Bronx, New York in 2013. Following her residency, She completed a fellowship in brain injury medicine at the JFK Johnson Rehabilitation Institute in Edison, New Jersey. She is board certified in Physical Medicine and Rehabilitation as well as Brain Injury Medicine. She is a staff physiatrist in the traumatic brain injury program at Hennepin County Medical Center in Minneapolis, Minnesota. Dr. Park is an assistant professor and a site director for resident rotation and clerkship in the Department of Physical Medicine and Rehabilitation at Hennepin County Medical Center/University of Minnesota Medical School.

Susan Schultz, MD
Professor of Psychiatry, University of Iowa Carver College of Medicine

Dr. Schultz is Professor of Psychiatry at the University of Iowa Carver College of Medicine. After receiving her MD in 1990 from the University of Nebraska Medical Center, she completed residency training at the University of Iowa followed by a research fellowship in the Neurobiology of Psychosis. She joined the University of Iowa faculty in 1995, and has conducted research on the treatment of dementia and psychiatric disturbances in late life, as well as brain imaging in persons with memory changes. She has board qualifications in Geriatric Psychiatry and Psychosomatic Medicine from the American Board of Psychiatry and Neurology. Her present research involves studying the brain changes seen in Alzheimer’s disease through brain imaging and other biological markers. She has conducted experimental treatment studies for Alzheimer’s disease through collaboration with the Alzheimer’s Disease Cooperative Study, a national study exploring new ways to diagnose and treat dementia.

Ana Durand-Sanchez, MD
Assistant Professor of PM&R, BCM

Dr. Durand-Sanchez is a PM&R / Brain Injury rehabilitation physician. She recently joined the PM&R department at the Baylor College of Medicine in Houston, Texas as an assistant professor. Dr. Durand-Sanchez has served on the board of directors of the Brain Injury Association of Indiana and the Faculty Development Coordinating Committee at IU. She received a medical degree from the University of Guadalajara School of Medicine in Mexico. Following completion of an internship at Montefiore Medical Center in New York, she trained in physical medicine and rehabilitation at the Baylor College of Medicine/The University of Texas Health Science Center PM&R Alliance in Houston, where she received the Oliver R. Smith Resident Achievement Award upon graduation.
Dr. Durand-Sanchez completed postdoctoral fellowships in Traumatic Brain Injury & Polytrauma, and in Advanced Brain Injury and Spasticity management, with a strong focus on research of motor recovery at UT-Houston. She has written scientific posters and papers for academic meetings and has participated in academic lectures and conferences in the United States and Mexico. She is an active member of several professional organizations, including the ACRM and the AAPM&R.

Dr. Durand-Sanchez was an invited researcher at the Indiana Center for Advanced Neurorehabilitation and continues to collaborate with its members. She was accepted into the Indiana University School of Medicine Independent Investigator Incubator program, which she completed in 10/2015. Her research focus is the rehabilitation and reintegration of individuals with acquired brain injuries using noninvasive brain stimulation, pharmacotherapy, and other techniques to promote motor recovery.